11 mature. It is quality that matters. I did get 4 chromosomally normal embryos from 3 cycles (we did PGS on day 6 blasts). think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. 2005-2023Everyday Health, Inc., a Ziff Davis company. With my day 6 u/s, the lupron was reduced to 5 units in the morning a, Hey, if you've done the EPP protocol, can you tell me more about it? Going with a microdose lupron protocol for my 2nd, starting on 11/30. BFP on FRER 5dp5dt: IN SHOCK! It is possible that the ovarian stimulation process on the egg donor would be shorter or longer than that shown above. [Sheri] What is DHEA? Clomid+ 150 iu follistim+150iu menopur and GH every other day. Estrogen priming and the agonist-antagonist conversion protocol is at least as successful as the microdose flare protocol based on medical data. I'm about to start a ton of supplements my nurse suggested to me. November IVF Protocol - DOR / LOW AMH / +40. Some background on our situation: Is this normal??? No MFI at all. He's also prescribed microdose lupron, gonal, low dose hcg, and pregnyl. We retrieved 8 eggs and 8 were fertilized. I just pray it works. Setting: Anatolia Women and IVF Center. The use of MCDL can improve the patient's response to gonadotropin therapy. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. I am not familiar with it, but I will definitely some research. Others involve newer supplements such as DHEA, and still others involve the use of injectable medications such as growth hormone. Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. I did this protocol for my cycle. In 2018 after 4 rounds of ivf I had my daughter. Just curious-What was your medicine protocol. undefined will no longer be visible to you including posts, replies, and photos. I am a little concerned that I am supposed to take 300 iu's of Gonal-F. 3F. In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. -We're both. Only thing I can pinpoint is age. I feel like it's always better to go slow & steady. Five days before her last BCP, she will start Lupron. I know I did Gonal-F because I'd never done it before (I was a follistim lady prior) - I can check tonight and see what it was. EDD 5/11/14, Jack dx at 19w1d with Dandy Walker on 12/16/13, Severe Pre-e /HELLP set in Jack born sleeping at 20w1d on 12/23/13, FET #2 --July 2014 BFP! 1 transferred and Im 22 weeks. The LDL protocol was initiated with late luteal lupron (0.25 mg daily). I miscarried the normal. It helps me keep the tiniest glimmer of hope alive! Use of this site is subject to our terms of use and privacy policy. One ended up with one pgs normal (but my numbers were cut down by needing to pgd as well so we had to discard at least one euploid in this cycle) Next try I got 13 eggs, I think 8 fertilized, we sent 5 good/excellent blasts off and got 2 more pgs/pgd normals. 0000001323 00000 n 1 single dose LUPRON-at RE office Bzeety & Hootie- you guys give me sooo much hope, seeing that you both had success with this protocol after being through the ringer so many times. Instead, we've had two "highly unusual" experiences and I could really use some input. Started with our current RE in April 2017; diagnosis is unexplained infertility (everything came back fine for both me and my husband on all tests). Group Black's collective includes Essence, The Shade Room and Naturally Curly. . From what I've read on the boards, the start of FET prep typically begins 30 days after Injection #2. That is the reason why we are doing IVF. I am starting on my fourth mini stimulation IVF and am looking for any insight into my situation, words of encouragement of those in a similar position or anyone that has experience with the Estrogen Priming Protocol. Have questions about navigating your Inspire support community or need assistance from one of our Inspire Moderators? Lupron flare was a winner for me, for sure. Please specify a reason for deleting this reply from the community. Reply with more details about your situation and I'm sure other gals on the site here will respond with their advice more specific to your situation. I feel like this entire experience has been a series of problem found, problem solved, and another problem found. (I did not use a lot of what was ordered.) This is how my current clinic intends to proceed. I am currently priming with growth hormone waiting for my period. In summary, ovarian stimulation is a very complex process. The major difference is that, by cutting the dose of Lupron down to one sixth of the routine dose, and by giving it twice daily, the Lupron actually turns the pituitary gland on rather than off, producing major release of FSH. I'm super excited for you, yay!!! You had a cyvle with 11 eggs. I had my first cycle canceled due to poor response to stims and ovulating through the lup.. My next cycle will be with EPP no BCP, but keeping the same Lup. Go back for a check on Thursday. With IVF#2, I got 16 eggs, 15 of which were mature. MENTS..I am now 17 wks pg from that cycle. 0000000960 00000 n My second we moved from an antagonist to a Lupron stop protocol with PICSI and wound up with 8 embryos, 3 of which were PGS normal. Me: 33, Endocrine issues & FVL DH:32, Nothing. My last two cycles resulted in only one embryo viable for testing which in the end were aneuploid. 28 years old, first IVF cycle cancelled?! estrogen priming is just another way to avoid cysts and quiet your ovaries before starting stim. Micro-dose Leuprolide injection (MCDL) is a compounded preparation made from diluted commercially available leuprolide. It's not your first rodeo here." What's weird is all of my levels are normal and i'm so young so i think the doctor and nurses are all perplexed as to how my egg quality was so bad! On the other hand, the Long Agonist protocol can't use Lupron as the trigger because it already deploys Lupron elsewhere. Def try the microdose lupron flare and let us know how it turns out!!!! Then 2X10U Lupron and 2X225U Gonal-F per day for 10 days. Experience with Estrogen Priming Protocol? During a short protocol, Lupron is first introduced during the stimulation phase. Yeah I was a poor responder my last cycle and i was on a lot of lupron. Ugh, this totally blows!!!! 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. Hello all, I need some feedback. The retrieval resulted in 8 eggs with the microdose lupron protocol. Final u/s showed 5 follicles, stimmed for 2 weeks but ovulated all during retrieval. Hello, I wanted to try this one a while back, but my RE wasn't keen. What was your protocol before? What I have seen in my years of fertility groups for women with DOR is that it seems many of our bodies like femara. ?Put back 2 day 5 embryos and now I am here. Because my follicle growth was so dysfunctional during my first round my doctor has decided to try a microdose lupron flare protocol starting with 5 weeks of birth control which ends on Monday. So- that's what's going on. Both hCG and Lupron effectively trigger maturation, (necessary for IVF success), but Lupron is better tolerated. 43 doing mini-IVF, does this protocol look good? . Sounds like CC.RM is doing EPP Oprah-style. April '14 Planning IVF attempt #3. I am not familiar with it, but I will definitely some research. Approximately fifteen years ago, a different type of GnRH analog was developed. I really believe that its a miracle protocol for those who are poor responders. [curious1] lcurtis8, it's a hormone that we produce plentiful as younger adults; as we age it decreases. Once down regulation was obtained, the lupron dose was decreased to 0.125 mg daily and gonadotropin stimulation was initiated. Jo, have you heard of the estrogen priming protocol? Design: Retrospective, case-control study. Then on stimming day 6, they found 18 follies. We use during the pill from person through luteal phase. I just started a new one with estrogen priming, microdose, letrozole and only gonal f. No menopur. It goes by several different names, including the Lupron overlap protocol or the long down regulation protocol, but the basic concept is that the pituitary gland is suppressed, the ovaries are stimulated, and the uterine lining is supported in that order. I just got my calendar today and I'm getting ready to start Lupron. Following. Please share your stories..how long did you stim for? hi, I did it at age 38. Also plenty of cases in this board and other places where women only have 4 eggs retrieved and get a normal. They have me on Follistim, Low Dose HCG, and Ganirellex. Long Lupron protocol. In addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. My first 2 retrievals were in 2014, 2016 which were just egg freezing cycles and I cannot access them.now due to covid. (Not so) Short summary - DH and I have been ttc since May 2015, two early m/c. Usually it is started and then followed the next day by adding in FSH and LH injections. I have low thyroid, endometriosis, blocked tubes & diminished ovarian reserve. But I'll let you know if I respond better! As stated above, this protocol is the most commonly used regimen, both in the US and in our practice. Curious to see if anyone has had success using the long lupron protocol with DOR? . Our patients visit Texas Fertility Center to achieve their dreams of having a baby. Find advice, support and good company (and some stuff just for fun). Has anyone done this Lupron STOP protocol? Thoughts on different protocols? My little one is a success story from MDL! Does anyone have any advise or success stories about this protocol. Of course that wasn't the only thing we changed but it is what I think helped me get more eggs that I've ever had before (37! And Yay for no BCP, I hate that stuff, I've done all the different methods with the exception of EPP. I'm reading so much about low stim for DOR and over 40 works better that make me very nerveous about trying high doses. I had 6 unexplained failure FETs. Infertility Support Community in Partnership with RESOLVE. My RE wants to use a lupron microdose protocol. 8Cell 1Grade 2Embies. Long awaited FET on 9/3. Have done 3 IUI's - 2 w. clomid and 1 with Gonal - F. I had a hyrdo on my left tube which had been removed and no left ovary to be found :( But I do have a good right tube & ovary. Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. Infertility Support Community in Partnership with RESOLVE. IVF 1 - on BCP protocol. Wowzers!!! Your nurse will phone you with instructions by 5:00PM this day. So we didnt biopsy & test then freeze. When the largest follicle(s) reaches 18-20 mm in average diameter, the eggs are ready to be undergo the last step in their maturation process, and a single injection of hCG is given. Im 42, have DOR and my AMH is .90. IVF1 (ICSI): Long Lupron Attempt #2 is going much better. Lupron Depot is used in women to treat symptoms of endometriosis (overgrowth of uterine lining outside of the uterus) or uterine fibroids. Your post will be hidden and deleted by moderators. They are concerned about egg quality. 0000017388 00000 n What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. This educational content is not medical or diagnostic advice. I didn't respondall thatwell to my Follistim-Ganirelex protocol during IVF #1 and my RE told me today he's going to try this for #2. For those women whove had more than one ivf cycle, did you change protocol? Beta 1/22: 14 Beta 1/24: 24 Beta 1/26: 28 With IVF#1, I only got 2-3 mature follies. Austin, Texas 78731, 16040 Park Valley Drive Building 1, Ste 201 9 eggs retrieved, 2 fertilized with ICSI, 1 arrest on day 3, the other arrested on day 5. Does any have any experience or feedback with this treatment plan?? Good luck! I am going in for my 4th IUI in what was supposed to be an IVF cycle. Success with Long Lupron Protocol for DOR ? Have the embryos tested for sure and if itdoesnt work out I will give you all the info for embryo adoption. Utilizing advanced tools and technologies, our doctors take on the toughest cases, providing renewed hope for would-be parents. Stimulation Day 4 Come in for an E2 and LH blood test. It seems many of our Inspire Moderators 6 blasts ) Beta 1/22: Beta... Gonal f. no menopur to treat symptoms of endometriosis ( overgrowth of uterine outside! 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Starting on 11/30 medical data for at least as successful as the microdose flare protocol based medical... One of our bodies like femara or longer than that shown above testing which in the end aneuploid. Resulted in 8 eggs with the microdose flare protocol based on medical data deleted by estrogen primed microdose lupron flare protocol karela know if I better...